Animal Models and Physiology Core – Services

The Core offers:

  • Distribution of genetically modified mice (MIP-GFP, MIP-Luc, MIP-CreER and others)
  • Advice, training and service in metabolic phenotyping of mice (glucose and insulin tolerance testing, metabolic cage studies (TSE LabMaster Metabolism Research Platform), body composition by DEXA
  • Advice, training and service in generating diabetic mouse models using streptozotocin and partial pancreatectomy
  • Advice, training and service in islet transplantation into mice (intraportal and kidney capsule)
  • Advice, training and service using imaging and image analysis for large-scale analysis of beta-cell mass, islet size distribution, islet cellular composition and islet vasculature of mouse, pig and human pancreas