Pilot & Feasibility Grants

Past Awardees

2010-2011 (Year 34)

  1. Marvin Makinen, D.Phil.: "An Uncompetitive Inhibitor of PTP1B as a Lead Compound for Drug Discovery"
  2. Abraham Palmer, Ph.: "Role of Glo1 in the Behavioral and Psychological Aspects of Diabetes"
  3. Namratha Kandula, M.D., M.P.H. (Northwestern): "Get Diabetes RITE (Retention, Integration, Transfer, Everyday Self-Management)"

2009-2010 (Year 33)

  1. Arshiya Baig, M.D., M.P.H.: "Health and Faith Working Together to Control your Sugar"
  2. Robert Keenan, Ph.D.:  "A novel post-translational membrane protein targeting pathway: new targets for insulin-related diseases"
  3. Kay Macleod, Ph.D.:" Regulation of Lipid Metabolism and Obesity in BNip3 Null Mice"
  4. Jayasri Nanduri, Ph.D.: "Intermittent hypoxia and beta-cell function"
  5. Betty Soliven, M.D.: "Myelin PO and peri-islet Schwann cells in diabetes and neuropathy"

2009 (ARRA supplement)

  1. Mary Kinkel, Ph.D.: "The role of Retinoic Acid in beta-cell function"
  2. Nissim Hay, Ph.D. (UIC): "Leptin deficiency undelies diabetes in Akt-deficient mice"
  3. William Lowe, M.D. (Northwestern): "Beta Cell Mass in Pregnancy 3D Imaging and a Novel Transgenic Model"
  4. Laurie Quinn, Ph.D. (UIC): "Diabetes and Cardiovascular Risk Among Asian Indian Adolescents "

2008-2009 (Year 32)

  1. Stephen Kent, Ph.D.: "Using Chemistry to Study Folding Mutations in Proinsulin"
  2. Martin Kreitman, Ph.D. and Michael Ludwig, Ph.D.: "A Fly Model to Investigate Diabetes"
  3. Wanqing Liu, Ph.D.: "A genome-wide association study (GWAS) to identify the genetic determinants of the human intrahepatic fat content"
  4. Xiaoxi Zhuang, Ph.D.: "The dual role of leptin in food seeking; Ali Cinar (IIT) Specific Glucose Prediction Models and Automatic Insulin Pump Controllers"
  5. Sue Penckofer, R.N., Ph.D. (Loyola): "Vitamin D for Metabolic Control and Depressive Symptoms in Women with Diabetes "

2007-2008 (Year 31)

  1. Michael Grassi, M.D.: "Diabetic Retinopathy Genetics"
  2. Piers Nash, Ph.D.: "Physiological Ligand Specificity and High-Resolution Interaction Mapping of SH2 domains in the Insulin & IGF-1 Receptor Systems"
  3. Dan Spergel, Ph.D.: "Calcium Signaling in the Hypothalamic Control of Blood Glucose and Food Intake"

2006-2007 (Year 30)

  1. Nobrega, Marcelo A., Ph.D.: "In vivo reagents to study the role of TCF7L2 in glucose homeostasis and diabetes"
  2. Wicksteed, Barton L., M.D. Ph.D.: "What preproglucagon gene promoter sequences direct islet α-cell gene expression?"

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2005-2006 (Year 29)

  1. Peek, Monica, E., M.D., M.P.H.: “Racial Discrimination and Decision-Making Among African-Americans with Diabetes”
  2. Grdina, David, Ph.D.: “Induction of Antioxidant Enzymes in Pancreatic B-cells by Non-Protein Thiols.”
  3. Hara, Manami, D.D.S, Ph.D.: “Culture Conditions that Target Embryonic Stem Cells to Differentiated Beta-Cells”
  4. Tasali, Esra, M.D.: “The Role of Heritability of Slow Wave Activity in the Predisposition to Diabetes”

2004-2005 (Year 28)

  1. Pannain, S.: “Sleep: The Effect on Appetite and Carbohydrate Metabolism”
  2. Kim, J.: “Role of 11beta-HSD1 in Hepatic Glucocorticoid Action”
  3. Tang, W.-J.: “Domain Organization and Structure of Insulin Degrading Enzyme”

2003-2004 (Year 27)

  1. Cohen, Ronald, M.D.: “Role of Corepressors in Adipogenesis”
  2. Lipton, Rebecca, Ph.D.: “Overcoming Barriers to Diabetes Self-Management for Older Adolescents and Young Adults”
  3. Solway, Julian, M.D.: “Vitamin D Receptor Transgenic Mice as a Model of Obesity and Diabetes”

2002-2003 (Year 26)

  1. Holper, Elizabeth, M.D.: “Growth Factors and Collaterals in Diabetes Mellitus”
  2. Huang, Elbert S., M.D.: “Older Diabetes Patients’ Preferences Regarding Multiple Treatments and Prevention”
  3. Li, Yan Chun, Ph.D.: “Vitamin D Receptor Transgenic Mice as a Model of Obesity and Diabetes”
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2001-2002 (Year 25)

  1. Baumann, Elizabeth, M.D.: “Insulin Resistance as a Childhood precursor of Polycystic Ovary Syndrome”
  2. Brady, Matthew J., M.D.: “Modulation of Glycogen Metabolism in Murine Adipocytes”
  3. Burnet, Deborah, M.D.: “Children’s Diabetes Prevention Program”
  4. Garfinkle, M.: “Measurement of Pancreatic Beta-Cell Number”
  5. Hara, Manami, M.D.: “Measurement of Pancreatic Beta-Cell Number”
  6. Hoff, Houter, M.D.: “Role of the Insulin Receptor in the GnRH Neuron”
  7. Wolfe, Andrew, Ph.D.: “Role of the Insulin Receptor in the GnRH Neuron”
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2000-2001 (Year 24)

  1. Fu, Yang-Xin, M.D., Ph.D.: “Lymphotoxin and Islet Transplantation” (NIDDK Supplement Program)
  2. Hoff, Wouter, Ph.D.: “Self-Calibrated Fluorescent Glucose-Sensing Fusion Proteins” (NIDDK Supplement Program)
  3. McNally, Elizabeth M., M.D., Ph.D.: “Cardiovascular Function Mediated by the Sulfonylurea-2 Receptor”
  4. Yuan, Chun-Su, M.D., Ph.D.: “Anti-Diabetic Effects of Ginseng Extracts”
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1999-2000 (Year 23)

  1. Di Rienzo, A.: “Population Genetics of Two Loci Contributing to Type II Diabetes Susceptibility”
  2. Levi-Setti, R.: “Ion Microprobe Imaging of Pancreatic Tissues”
  3. Makinen, M.: “Insulin Mimetic Effect of Vanadyl”
  4. Nelson, D.: “Molecular Analysis of the Pancreatic Islet Ca++ Activated Chloride Channel”
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1998-1999 (Year 22)

  1. Bishku, D.: “A Web-based Interactive Computer Program for Diabetes Education”
  2. McNally, E.: “Mechanisms of Cardiac Hypertrophy in Diabetes”
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1997-1998 (Year 21)

  1. Houamed, K.: “Molecular Physiology of Pancreatic C++ Activated K+ Channels”
  2. Li, W.: “The Role of p62dok (Downstream of Tyrosine Kinase) in Insulin Receptor Signaling”
  3. Schwartz, E.: “Control of Vesicle Cycling in Pancreatic Beta-Cells”
  4. Soliven, B.: “Signal Transduction in Glia: Role of Lipid Mediators”
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1996-1997 (Year 20)

  1. Ashton-Rickardt, P.: “Thymic Selection of Diabetes Causing T Lymphocytes”
  2. Birkenbach, M.: “The Role of EGR-1 in Beta Cell Responses to Glucose”
  3. Meltzer, D.: “Does Quality-Adjusted Life Expectancy Predict Preferences”
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1995-1996 (Year 19)

  1. Baum, C.: “The Role of SCP-2 in Diabetes Associated Hypercholesterolemia”
  2. Chin, M.: “Physician Specialty, Socioeconomics, and Diabetes”
  3. Roe, M.: “Identification of SERCA Isoforms in Islets of Langerhans”
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1994-1995 (Year 18)

  1. Glick, B.: “Molecular Analysis of Golgi Organization”
  2. Graves, R.: “Regulation of the Adipogenic Transcription Factor, PPARy2”
  3. MacNicol, A.: “Raf-1 Regulation During Proliferation & Differentiation”
  4. Sperling, A.: “The Role of Costimulatory Molecule CD43 in T-Cell Activation”
  5. Zhang, J.: “P2-purinoceptor, A New Target for Antidiabetic Drugs”
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1993-1994 (Year 17)

  1. Aikens, J.: “Glycemic Effects of Stress Reduction in African Americans w/Type II Diabetes Mellitus”
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1992-1993 (Year 16)

  1. Sprague, S.: “Adynamic Bone Disease in Diabetic Renal Failure”
  2. Barr, E.: “Gene Therapy for Diabetes Mellitus”
  3. Bluestone, J.: “Modulation of Autoimmune Diabetes with Soluble Co-stimulatory Molecules”
  4. Meyer, G.: “Etiology of "Brittle Diabetes" and Applicability to General Diabetes Care”
  5. Hanck, D.: “Cloning and Expression of the Na+ Channels of Pancreatic Beta Cells”
  6. Kohrman, C.: “Diabetic Children and their Families:A Cross-cultural Study of Meanings and Implications”
  7. Zeng, Y.: “Intrathymic Islet Xenotransplants: Mech Immunoreactions”
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1991-1992 (Year 15)

  1. Burant, C.: “Structural Determinants for Subcellular Localization of Glucose Transporters in Polarized Cells”
  2. Buse, J.: “The Role of Peptide Transporters in the Pathogenesis of IDDM”
  3. Davis, B.: “Modulation of Hyperglycemia-Induced Fibronectin Gene Expression and RAF Activiation”
  4. Rudberg, M.: “Diabetes Chart Audit Instrument for Geriatric Care”
  5. Segev, N.: “Role of GTP-Binding Rab Proteins in B-Cell Function”
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1990-1991 (Year 14)

There were no newly funded awards.

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1989-1990 (Year 13)

  1. Sant, A.: “Molecular Analysis of Antigen Presentation by Pancreatic Islet Cells”
  2. Miller, J.: “The Role of Islet Specific Class II Expression in IDDM”
  3. Schoeller, D.: “Etiology of Hypertriglyceridemia in NIDDM”
  4. Nelson, D.: “Excitation-Secretion Coupling in a Model B-Cell Line”
  5. Fox, A.: “Secretory Cells: Calcium Channels-Stimulus Secretion Coupling”
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1988-1989 (Year 12)

There were no newly funded awards.

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1987-1988 (Year 11)

  1. Brasitus, T.: “Diabetic-Induced Alterations in Rat Intestinal Membranes”
  2. Bluestone, J.: “In Vivo Effects of Monoclonal Anti-T Cell Antibodies”
  3. Scanu, A.: “Lipoprotein(a) in Hypertriglyceridemia and Diabetes”
  4. Rosner, M.: “Expression of Drosophila Insulin-Degrading Enzyme”
  5. Cara, J.: “Role of Insulin in the Androgen Production by Rat Ovarian Theca-Interstital Cells”
  6. McNabb, W.: “Lifestyle Modification Project: PATHWAYS”
  7. Herold, K.: “Islet Reactive T-Lymphocytes in Non-Obese Diabetic Rats”
  8. Davidson, N.: “Intestinal Lipoprotein Assembly: Modulation by Diabetes Mellitus”
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1986-1987 (Year 10)

All three Pilot and Feasibility studies from year 09 were funded for a second year. Four Pilot and Feasibility studies from year 08 were funded for a third year (Nakao, Palfrey, Steck, Villereal). There were no new awards.

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1985-1986 (Year 9)

  1. Borow, K.: “Diabetic LV Dysfunction; Muscle or Autonomic Abnormality”
  2. Robertson, G.: “Role of Vasopressin in Platelet Abnormalities in Diabetes Mellitus”
  3. Thistlethwaite, J.R.: “Passenger Cell Depletion from Intact Pancreases”
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1984-1985 (Year 8)

  1. Bashook, P.: “Instrument Validation to Identify Influential Physicians”
  2. Beneveniste, R.: “Plasma Free ACG-Alpha Subunit in Diabetic Pregnancy”
  3. Nakao, M.: “Altered Regulation of Growth Hormone in Diabetes”
  4. Palfrey, H.: “Role of Calmodulin Binding Protein in Insulin Secretion”
  5. Steck, T.: “Band 3 Tyrosine Kinase in Erythrocyte Membranes”
  6. Villereal, M.: “Cell Physiology of Pancreatic Beta Cell Secretion”
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1983-1984 (Year 7)

  1. Cohen R. and M. Powers: “Dieticians Involvement in Care of Diabetic Patients”
  2. Meredith, S.: “Non-enzymatic Glycosylation of Basement Membrane Proteins in Diabetic Glomerulopathy”
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1982-1983 (Year 6)

  1. Drickamer, K.: “Biosynthesis and Gene Structure of a Membrane Receptor”
  2. Chang, E.: “Diabetic Diarrhea and Disturbed Autonomic Regulation of Fluid Transport”
  3. Fuchs, E.: “Alterations in Epidermal Growth Patterns by Peptide Hormones”
  4. Gewertz, B.: “PGE, Infusion in Ischemic Diabetic Extremities”
  5. Karl, R.: “Transport Mechanisms in Beta Cell”
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1981-1982 (Year 5)

There were no newly funded awards.

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1980-1981 (Year 4)

  1. Favus, M.: “Vitamin D Metabolism in Diabetes Mellitus”
  2. Frohman, L.: “Blood-Brain Barrier and Neuroendocrine Regulation in Diabetes Mellitus”
  3. Miletich, D.: “Cerebral Ketone Metabolism in Diabetic Goats”
  4. Schiffer, M.: “Diabetic GBM Studied with Monospecific Antibodies”
  5. Schoenberg, H.: “Vesical and Sexual Dysfunction in Diabetes Mellitus”
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1979-1980 (Year 3)

There were no newly funded awards.

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1978-1979 (Year 2)

  1. Berelowitz, M.: “Somatostatin Physiology in Diabetes Mellitus”
  2. Getz, G.: “Low Density Lipoprotein Turnover in Diabetes”
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1977-1978 (Year 1)

  1. Frohman, L.: “Biochemical & Physiological Studies on Neurotension”
  2. Levitsky, L.: “Pathophysiologic Correlations in Autoimmune Diabetes”
  3. Reckard, C.: “Sequelae of Pancreatic Islet Transplantation in Rats”
  4. Rudd, P.: “Prognostic Stratification in Ambulatory Diabetic Management”
  5. Skosey, J.: “Studies on the Immunopathogenesis of Vascular Disease in Diabetes Mellitus”
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