Maryellen L. Giger's research interests include digital radiography and computer-aided diagnosis in breast imaging, chest/CT imaging and bone radiography. In the field of breast cancer, she is currently investigating computerized methods with which to aid radiologists/oncologists in determining the likelihood of malignancy and in predicting patient prognosis using multi-modality images of the breast. She is also developing computerized radiographic markers for assessing breast density and parenchymal structure that may be used together with clinical markers for use in determining risk of cancer and monitoring response to treatment. Another area of her research involves the investigation of new computerized radiographic image analysis methods for assessing risk of fracture and osteoporosis. In collaboration with Dr. Favus, the natural history of metabolic bone disease in a variety of disorders including diabetes will be determined.